OrgCan - Patient Derived Cancer Organoids
Revolutionizing Cancer Drug Discovery: Patient-Specific Insights for Targeted Therapies. In the fight against cancer, one size rarely fits all. OrgCan, Biodimension's cutting-edge platform, empowers you with patient-derived cancer organoids (PDCOs), offering a powerful and translational in vitro system for truly personalized drug development.
Harness the Power of OrgCan
OrgCan organoids are directly derived from patient tumor biopsies, faithfully preserving the unique genetic, genomic, and phenotypic characteristics of the original cancer, providing unparalleled patient relevance for drug discovery.
Key Benefits
Unparalleled Patient Relevance
OrgCan organoids are directly derived from patient tumor biopsies, faithfully preserving the unique genetic, genomic, and phenotypic characteristics of the original cancer.
Predictive Preclinical Models
Screen drug candidates in a system that mirrors individual patient tumor biology, leading to more accurate predictions of clinical response and reduced attrition rates.
Accelerate Drug Discovery
Streamline your preclinical pipeline by identifying promising drug candidates and understanding resistance mechanisms in a patient-specific context.
Personalized Medicine Strategies
Develop and validate targeted therapies tailored to the specific molecular profile of individual patient tumors.
Study Tumor Heterogeneity
Investigate the diverse cellular populations within a single tumor and their differential responses to treatment.
Explore Novel Biomarkers
Identify predictive and prognostic biomarkers associated with drug sensitivity and resistance in patient-relevant models.
Breast Cancer Spheroids
Breast cancer, with its diverse presentations and intricate pathways, has long challenged researchers seeking effective therapies. Traditional models, while valuable, often fall short of capturing the full tumor microenvironment and intricate interactions responsible for its aggressiveness.
Organoids faithfully recapitulate the architecture and genetic diversity of human breast cancers. These living models, meticulously crafted from patient tissues, hold the key to unlocking new avenues for drug development. No longer confined to simplified cell cultures or animal models, researchers can now study drug response in an environment that closely mirrors the complexities of actual human tumors.
Treatment Response Studies
CANCER
Patient-derived cancer organoids
NORMAL
Healthy tissue organoids
Research Applications
Explore the diverse applications of OrgCan organoids in cutting-edge cancer research and drug development.
High-throughput Screening (HTS)
Identifying novel drug candidates with anti-cancer activity from large compound libraries.
Drug Toxicity Assessment
Examining the impact of drugs on cancer cells within the organoid model for safety evaluation.
Predictive Biomarkers
Correlating organoid drug response with patient profiles to discover sensitivity or resistance markers.
Tumor Microenvironment (TME)
Co-culturing organoids with immune cells, fibroblasts, and endothelial cells to investigate interactions.
Models We Are Building
We are developing comprehensive panels of patient-derived organoids to provide consistent models throughout your research journey.
Breast Cancer Panel
Comprehensive patient-derived organoid collection
We are developing a panel of 15 patient derived organoids for tumor heterogeneity and consistent models throughout your research journey. This comprehensive collection enables researchers to study the diverse presentations of breast cancer and develop targeted therapeutic strategies.
Key Features:
- 15 diverse patient-derived organoids
- Tumor heterogeneity representation
- Consistent models for long-term studies
- Drug response characterization
Liver Organoids
Focused for better clinical relevance
Our liver organoids are specifically designed for enhanced clinical relevance with comprehensive panels of patient-derived organoids (PDOs). These models provide accurate representation of liver function and disease states for drug metabolism and toxicity studies.
Applications:
- Drug metabolism studies
- Hepatotoxicity assessment
- Liver disease modeling
- Clinical translation studies
Customizable Solutions
Biodimension offers flexible services, from organoid generation and expansion to customized drug screening assays and multi-omics analysis. We create cancer panels for you and any type of cancer organoids can be developed with OrgCan.
Services
- • Organoid generation
- • Expansion & maintenance
- • Drug screening assays
- • Multi-omics analysis
Capabilities
- • Custom cancer panels
- • Any cancer type
- • Patient-specific models
- • High-throughput screening
Support
- • Expert scientific support
- • Data analysis
- • Protocol optimization
- • Quality assurance
Biological Sample Repository
We bank biological samples valuable resources for bio-medical research, drug development and personalized medicine. Our biobank is committed to research and precision medicine by providing high-quality biological specimens and data to the scientific community.
Products
Ready to Revolutionize Cancer Research with OrgCan?
Discover how OrgCan's patient-derived cancer organoids can accelerate your drug development and precision medicine initiatives with unparalleled patient relevance.